On "big nights out" (about once a month) friends of mine "plug" ecstasy tablets — by which I mean they each stick one up their butt instead of swallowing.

They claim that is a "safer" way to ingest E because it bypasses the liver and goes right into the bloodstream. They also claim the effects are heightened.

I have been tempted to try this method as they swear by it, but thought I'd get your opinion first — are there any potential side effects to plugging? Is it really a "safer" way to use E?

Recently, I have heard about a new hallucinogen available called salvia dinorium. Some of my friends have tried it and they tell me it is an incredible experience and that when you hallucinate, you have the perception of being brought back in time. Before I even think about trying this, however, I would like to have a more precise idea of what the effects are and what the possible risks of taking salvia are.

I am curious about the effectiveness of ketamine for therapy and recovery of drug use in young people/teenager in depression and success rate.

Hi, where can I test my molly on or near campus?

Is lsd safe to use while on an SSRI.

Me and my friends are users of X. We know that it's illegal and not good for you, but it's only a once in a while thing. My question is that I know there are different types of X pills that you can take. We have been getting motorolas and I know a friend told me that mitsubishis are really bad to take. I was wondering the differences between the pills and the differences between triple and double stacked pills......

1) What are the long-term and short-term effects of abusing NyQuil? I've heard it's very dangerous to use it recreationally, but I'm not sure what's dangerous about it. I've heard you can even die from abusing it.

2) I have recently just finished my first year in college and on a few occasions, a couple of friends and I had decided to drink massive amounts of Robitussin DM (dextromethorphan, I believe). It was fun, but the day after I felt like I was hit by a car! They call it robo trippin'. I have no intentions on doing this again; however, I was wondering if there were any long-term effects of it.

I have been doing weed for about six months now and on occasion a few other drugs. I usually do it only on average three times a week and a lot more on the weekends. I feel that it is ruining my life because my concentration is terrible and my marks have dropped significantly (20 points). I feel like I'm in a dream all the time and it just isn't fun anymore. I have heard that pot is not addictive but I have tried to stop but I feel sick and irritable if I don't smoke up. I have realized I need to quit but I can't. Why can't I stop if this "soft drug" is not addictive? Am I crazy? Please help. I want my life back. Thank you so much.

I heard that the first reaction you have to taking ecstasy is to become violently ill, after which the party can continue. This sounds like an urban legend to me. Could you clarify please?

I am a 23 year old female who enjoys a few glasses of wine but, in my opinion, doesn't drink more than the average college student. A few weeks ago, I had quite a bit to drink and haven't felt the same since. I am dizzy, forgetful, confused and my liver is very tender to the touch. I have continued to have a few glasses of wine a couple nights out of the week and it seems to be the only thing that gets me back to feeling "normal." Is this a normal way to feel or should I be concerned?