I recently went to my doctor because I've been unable to lose weight. I've been on a successful diet, accompanied with a reasonable exercise plan, but I've seen no real results. A series of tests were run — I've got optimum blood pressure, low cholesterol, and I am not diabetic. But, when my cortisol levels were checked — they were very high. The doctor suspected there was a possibility that I might have Cushings' Syndrome — but another test was run and that came up negative.

I was doing research on the internet, and I found that there was a link between excessive cortisol and depression. I was diagnosed with clinical depression when I was 12 (I am now 21). And I am currently untreated. What is the link between cortisol levels and depression? Are excessive cortisol levels a physical manifestation of depression? Or does an excess of cortisol for some other reason cause depression? Does an excessive amount of cortisol cause weight gain, or in my case prohibit weight loss? And if there is a connection — will treatment for my clinical depression (in the form of prescription pills) help me?

I've been unable to find answers anywhere, or at least a good source to tell me to stop worrying — any help would be appreciated.

Thank you for everything, and it is being appreciated by thousands. I have read all your advice to others and have learned a lot. However, I have a problem that I do not know how to handle. It started when I decided to turn myself around from being bisexual to straight (nobody knew what I was, except my best friend, who is also bisexual). I now have a big hole inside me that is being filled by the dark things of life (such as hatred). I had good qualities, such as a great personality, being open-minded, and I would rather go through life without it than turn back to the "bad" habits (please do not get me wrong, I will never judge gays for I have been close to being one). Please help me to fill the hole with life, to get back or improve on my qualities, and to gain the knowledge to approach and attract someone of the opposite sex. And one last thing, do you think it is wise to let my future girlfriend know what I used to be?

I really don't know what to call my situation. Some people say I was molested, others say I was sexually assaulted in the third degree, and others call it sexual misconduct. But when I was thirteen years old, I was touched by a fifteen-year-old boy on the bus for six months. I didn't want this or invite it. I would often fight and say no. He used to fondle my thighs and go into my pants. What is this called? Please e-mail me back.

My best friend has a weight complex. She constantly asks me if I think she's fat and even asks my boyfriend what he thinks of her weight. She isn't overweight and I just wish she would stop worrying about it all the time. Is there anything I can do to convince her she isn't fat?