Is there a connection between cortisol, depression, and weight loss?

I recently went to my doctor because I've been unable to lose weight. I've been on a successful diet, accompanied with a reasonable exercise plan, but I've seen no real results. A series of tests were run — I've got optimum blood pressure, low cholesterol, and I am not diabetic. But, when my cortisol levels were checked — they were very high. The doctor suspected there was a possibility that I might have Cushings' Syndrome — but another test was run and that came up negative.

I was doing research on the internet, and I found that there was a link between excessive cortisol and depression. I was diagnosed with clinical depression when I was 12 (I am now 21). And I am currently untreated. What is the link between cortisol levels and depression? Are excessive cortisol levels a physical manifestation of depression? Or does an excess of cortisol for some other reason cause depression? Does an excessive amount of cortisol cause weight gain, or in my case prohibit weight loss? And if there is a connection — will treatment for my clinical depression (in the form of prescription pills) help me?

I've been unable to find answers anywhere, or at least a good source to tell me to stop worrying — any help would be appreciated.


What can I do if I'm experiencing an aversion to sex with my long-term partner?

I've been with my boyfriend for just over 4 years. Our sex life has always been the strong thread in our relationship, even when we've had trouble in other areas. We both feel we are the best sexual matches we've ever had. But over the past 8 months things have slowly degraded on my end. He is still as excited as ever, but I just don't feel like it. When we try, I actually feel physically protective, as if blocking my body from a stranger, especially my breasts. It's like a physical compulsion to protect, but neither of us have a history of abuse in our relationship or outside of it, and his approach is loving and open. When he's clothed and we're not about to have sex I love holding him, being held by him, standing next to him, touching him, etc. I'm not physically repulsed by his body: I recognize that he's a ridiculously attractive man! I had some advice that I shouldn't force myself to have sex if I don't want to, but I've also heard the opposite: that I should stop thinking and just push through my body's shutdown. Most of the times when I do force myself I end up enjoying it, but that doesn't take away this "repulsion" feeling at the start. The worst thing is that he feels rejected and dissatisfied and keeps asking what he can do to turn me on. What to do?


Is my vegetarian diet making me feel tired?

I am a vegetarian and frequently feel like it takes a long time to "wake up" in the morning and some days I feel like I never quite get there. I can't help but think this may be diet related. I went to a doctor for a test for anemia which was negative and I always try to get a good nights' sleep (six to eight hours). In the past I have tried to gain weight and failed miserably. I remain a little underweight but get a good deal of exercise each day. Any ideas?


Why am I depressed as I navigate my sexuality?

Thank you for everything, and it is being appreciated by thousands. I have read all your advice to others and have learned a lot. However, I have a problem that I do not know how to handle. It started when I decided to turn myself around from being bisexual to straight (nobody knew what I was, except my best friend, who is also bisexual). I now have a big hole inside me that is being filled by the dark things of life (such as hatred). I had good qualities, such as a great personality, being open-minded, and I would rather go through life without it than turn back to the "bad" habits (please do not get me wrong, I will never judge gays for I have been close to being one). Please help me to fill the hole with life, to get back or improve on my qualities, and to gain the knowledge to approach and attract someone of the opposite sex. And one last thing, do you think it is wise to let my future girlfriend know what I used to be?


Are there health concerns associated with consuming Sucralose (Splenda)?

1) What are your thoughts regarding the use of Splenda as a sugar substitute? I have heard that the body is not able to metabolize this and that it is excreted through the urine. Do you have any current research on Splenda and the side effects? I realize it is a relatively new product. Thank you!

2) I searched the archives and found no information on Splenda or sucralose. Lately, it seems like Splenda is gaining popularity in the crowded sugar-substitute category. It seems too good to be true — measures cup for cup like sugar, you can bake with it and mix it into drinks, and it is made from sugar so it really tastes like sugar. My two questions are... is this a safe product, or are there some disadvantages with the product? And secondly, if it is very safe and versatile, why aren't more companies using it now?


Is reusing water bottles safe?

I started buying bottled water because it seemed to taste better. As an experiment, I tried refilling the empty bottles with tap water and refrigerating them. And I discovered that what I really liked was drinking chilled water out of the bottle. If no one else is using the bottles, how often do I need to wash the bottles out with soap as opposed to just re-filling them?