Is there a connection between cortisol, depression, and weight loss?

I recently went to my doctor because I've been unable to lose weight. I've been on a successful diet, accompanied with a reasonable exercise plan, but I've seen no real results. A series of tests were run — I've got optimum blood pressure, low cholesterol, and I am not diabetic. But, when my cortisol levels were checked — they were very high. The doctor suspected there was a possibility that I might have Cushings' Syndrome — but another test was run and that came up negative.

I was doing research on the internet, and I found that there was a link between excessive cortisol and depression. I was diagnosed with clinical depression when I was 12 (I am now 21). And I am currently untreated. What is the link between cortisol levels and depression? Are excessive cortisol levels a physical manifestation of depression? Or does an excess of cortisol for some other reason cause depression? Does an excessive amount of cortisol cause weight gain, or in my case prohibit weight loss? And if there is a connection — will treatment for my clinical depression (in the form of prescription pills) help me?

I've been unable to find answers anywhere, or at least a good source to tell me to stop worrying — any help would be appreciated.


Is my vegetarian diet making me feel tired?

I am a vegetarian and frequently feel like it takes a long time to "wake up" in the morning and some days I feel like I never quite get there. I can't help but think this may be diet related. I went to a doctor for a test for anemia which was negative and I always try to get a good nights' sleep (six to eight hours). In the past I have tried to gain weight and failed miserably. I remain a little underweight but get a good deal of exercise each day. Any ideas?


Are there health concerns associated with consuming Sucralose (Splenda)?

1) What are your thoughts regarding the use of Splenda as a sugar substitute? I have heard that the body is not able to metabolize this and that it is excreted through the urine. Do you have any current research on Splenda and the side effects? I realize it is a relatively new product. Thank you!

2) I searched the archives and found no information on Splenda or sucralose. Lately, it seems like Splenda is gaining popularity in the crowded sugar-substitute category. It seems too good to be true — measures cup for cup like sugar, you can bake with it and mix it into drinks, and it is made from sugar so it really tastes like sugar. My two questions are... is this a safe product, or are there some disadvantages with the product? And secondly, if it is very safe and versatile, why aren't more companies using it now?


How can I prevent athletic performance anxiety?

I compete in an individual sport. The problem is that on the day of a major competition, I have really bad indigestion. Sometimes, I have to run to the bathroom every half hour for a bowel movement! Besides being annoying, disgusting, and a little embarrassing, this interrupts my competition and adds unneeded stress. Why is this happening and what can I do to prevent it?


Do I have obsessive-compulsive disorder (OCD)?

1) I think I might have OCD. I worry about it a lot and I want to go to a doctor, but I am too afraid. Can you please tell me the symptoms of OCD. Thank you.

2) I think I might have OCD. Since I was about 12 or 13, I started thinking really strange thoughts. I always felt like there were eyes watching me. I know its irrational to think such a thing, and I know there aren't any, but I get this weird feeling there are. I have to cover my windows in dark colored papers and check for any holes in them regularly, so there isn't the tiniest hole for someone to peek through. I have shades as well, but I never feel like they're enough. I also have to regularly make sure my windows are locked, sometimes I'll lock and relock them a couple times until it feels like the lock worked. The same with my bedroom door, I will not sleep at night if my door is unlocked, and sometimes I relock it more than once, or even reclose my door more than once. It doesn't always feel like it properly shut the first time. I also have to turn any faces away from me. My stuffed animals can't look in my direction, and I wont hang pictures up in my room if it feels like it has eyes on it. I'm not scared of eyes necessarily, I know some people with beautiful eyes. I just can't take them staring at me. I also know they wont hurt me, either, but it feels as if somehow they will. I don't know how.

I'm really feeling like I might be going crazy. I'm stressed out beyond belief! Should I bring it up with my doctor? Should I get a therapist? Could this be OCD?