How do marijuana and Prozac interact?

I have two friends who were recently diagnosed with depression. They were both prescribed Prozac by their respective doctors. Both of them are heavy marijuana users and both failed to mention that to their doctors. One has been on Prozac for two months and the other for six weeks. I have noticed that their behavior has become strange: mood swings, paranoia, oversleeping, fatigue. They continue taking their Prozac (20 mg a day) and continue smoking pot. I am afraid that there might be some negative interaction between the substances, one being an antidepressant and the other a depressant. Can you provide some insight?


Do diet teas and meal-substitute shakes work to lose weight?

I've been trying to diet for over two years. My goal is to lose about 25 pounds, but the most I've been able to get is 15, and I can hardly keep it off. I concentrate on eating very little and since exercise is so hard to keep up, I pretty much starve myself to death. I manage to maintain the weight for a month, and then I lose control again. I've been thinking about the various diet products in the market, such as diet teas, herbs, meal- substitution shakes, and other medical products. I'd like to know what kind of side-effects they have, and how effective they are. (Some boast a seven-day plan, but that seems hardly believable.) Also, I'd like to know how well-researched the information is on these products (i.e., are they long-term enough to cover all the side-effects?) As for aspartame, is it really harmless, or is it just not researched yet?