Do you have some advice for someone suffering from low self-esteem? Some things that I struggle with: comparison of myself to others ("She is so "together!" Why am I not like that? What is lacking in me that makes her better?"), lack of faith in my abilities ("I'll never be as good as him at that — I might as well not try."), lots of self-criticizing ("Why did I sign up for this class — I should have known I couldn't handle it."), always saying yes to people or feeling like I've said the wrong thing... you get the idea. I've been feeling pretty unmotivated lately too, and I think this just adds to the problem. Can you give some advice, dear Alice?

I'm currently coming into my second year at a famous but huge university in a big, crowded city. My first year had its ups and downs, but I made a couple friends. The problem is, I commute, and I'm finding it hard socially. I've been depressed for the past year, thinking I'm regressing because I'm not meeting as many people as a normal student would. How does one go from meeting someone in class to hanging out with them on weekends? I feel like I am mostly the one initiating, so I feel like I'm imposing. In addition, the university is rigorous, so I don't always have the time to join the clubs. Any tips on how to make a lot of friends from classes even though I am not dorming?

I recently found out that I am being deployed. I am so concerned with it every minute of the day that I find myself becoming depressed and overwhelmed. What are some good ways to manage these anxieties?

What is the difference between grief and major depression? A few months ago, my boyfriend died in a car accident. Lately, I have been very depressed, but I am not sure if it is just part of the normal grief process or if it is depression.

The mother of one of my best friends from high school was diagnosed with liver cancer a few months ago. She is quite ill and in a lot of pain. She's been in and out of the hospital lately and things don't look so good. My own father was diagnosed with prostate cancer a year and a half ago, but he is really doing quite well (with medication, treatment, etc.). My friend's mother will probably be dead within six months to a year, so I'm not going through an immediate crisis.

My question is: What things should (and shouldn't) I be saying to, and doing for, my friend? I try so hard to be there for her but I really don't know what she's going through. She is very matter-of-fact about the fact that her mom is going to die. But I'm sure there's something I could be doing, isn't there? I hate feeling like I'm actually making her feel worse! Could you give me some idea of what she might be going through right now and how I could help? Even if it's a method for taking her mind off it occasionally (if that's a good idea).

How can I become more optimistic?

My oldest daughter died in a motor vehicle accident seven months ago. I have a husband and three other daughters. I am very depressed. Some days I think I won't make it. Some days I don't want to. I know that my life has been changed forever, but what can I do to help ease the pain — and to help me "move on" with my life?

It seems like me and several friends have been going through a bit of disappointment/boredom with life after graduation. I work long hours and am too tired to socialize like I did when I was in school. I was just wondering if there's such a phenomenon of post-college depression?